Category: Featured Publications
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Why We Need Community-Based Participatory Research (CBPR) in Neuroethics
Authors: Michelle T. Pham, Arynn de Leeuw, Ian Burkhart, Eran Klein and Sara Goering Publication: Neuroethics Date: April 8, 2026 Abstract: Empirical scholarship in neuroethics is steadily growing, adding greater context and complexity to conceptual and ethical debates Starke et al. BMC Medical Ethics 25:89, 2024. For example, qualitive studies have been used to understand…
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The Spatiotemporal Structure of Neural Activity in Motor Cortex during Reaching
Authors: Ryan A. Canfield, Tomohiro Ouchi, Hao Fang, Beatrice Macagno, Lydia I. Smith, Leo R. Scholl and Amy L. Orsborn Publication: The Journal of Neuroscience Date: May 20, 2026 Abstract: Intracortical brain–computer interfaces (BCIs) leverage knowledge about neural representations to translate movement-related neural activity into actions. BCI implants have targeted broad cortical regions known to…
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Effects of non-invasive spinal cord stimulation on autonomic function in individuals with subacute spinal cord injury: A pilot clinical trial protocol
Authors: Ryo Nakahara,Sarah Nasson,Ellie Bieler,Emilee Putsche-Young,Benjamin Aguila,Jiayi Shen,Emma Chung,Laura Winston,Stephen Burns,Deborah Crane,Margaret Eugenio,Klaus Krogh,Andrei Krassioukov,Chet Moritz,Soshi Samejima Publication: PLoS One Date: April 20, 2026 Abstract: Spinal cord injury (SCI) at or above the thoracic sixth spinal cord level disrupts descending sympathetic and parasympathetic control, leading to severe autonomic dysfunctions including cardiovascular and pelvic organ function.…
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A large-scale optogenetic neurophysiology platform for improving accessibility in non-human primate behavioral experiments
Authors: Devon J. Griggs, Noah Stanis, Julien Bloch, Jasmine Zhou, Karam Khateeb, Shawn Fisher, Larry Shupe, Felix Schwock, Eberhard E. Fetz, Hesamoddin Jahanian & Azadeh Yazdan-Shahmorad Publication: Nature Communications Date: February, 2026 Abstract: Optogenetics has been a powerful scientific tool for two decades, yet its integration with non-human primate (NHP) electrophysiology has been limited due…
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Study design considerations in clinical trials testing transcutaneous stimulation for spinal cord injury
Authors: Guest, J. and Moritz, C. Publication: Spinal Cord Date: March, 2026 Abstract: The unique challenges of tSCS clinical trials necessitate innovative methodological approaches beyond traditional placebo-controlled designs. Sequential self-controlled designs, biomarker-guided studies, and adaptive trial methodologies offer scientifically sound alternatives that respect participant welfare while generating robust evidence. Future research should pursue dual paths:…
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Multimodal optical imaging and modulation with simultaneous electrophysiology through smart dura in non-human primates.
Authors: Hong, N., Montalvo Vargo, S., Hatanaka, G., Gong, Z., Stanis, N., Zhou, J., Belloir, T., Wang, R.K., Bair, W., Chamanzar, M. and Yazdan-Shahmorad, A. Publication: Adv Sci (Weinh) Date: January, 2026 Abstract: Multimodal neural interfaces that integrate electrical and optical functionalities are promising tools for neuroscientific and clinical applications that involve recording and manipulating…
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Cortical potentials evoked by stimulation of cervical vagus vs. auricular nerve: a comparative, parametric study in nonhuman primates.
Authors: Rembado, I., Ravan, M., Akerman, M., Sanchez, M.M., Bascoc, K.J., Birch, C., Boyd, H., Amoeni, B., Morse, A., Kemp, I., Hur, J.W., Perlmutter, S., Su, D., Sison, C., Fetz, E.E. and Zanos S. Publication: Brain Stimulation Date: March, 2026 Abstract: Stimulation of sensory vagal pathways is typically delivered via invasive, cervical vagus nerve stimulation…
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Customizable artificial simulator for developing, planning, and training personnel on neurophysiology and surgical procedures in non-human primates
Authors: Lydia I. Smith and Amy L. Orsborn Publication: Journal of Neuroscience Methods Date: December, 2025 Abstract: BackgroundNeuroscience researchers often surgically implant hardware into model organisms to measure and manipulate neural activity. Designing and optimizing these procedures in non-human primates often requires sedated or euthanized animals. Artificial tissue technologies can reduce animal use in this process, but existing simulators…
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Temporal basis function models for closed-loop neural stimulation
Authors: Bryan, M.J., Schwock, F., Yazdan-Shahmorad, A. and Rao, R.P.N. Publication: J. Neural Engineering Date: September 16, 2025 Abstract: Objective. Closed-loop neural stimulation provides novel therapies for neurological diseases such as Parkinson’s disease (PD), but it is not yet clear whether artificial intelligence (AI) techniques can tailor closed-loop stimulation to individual patients or identify new…
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Early intervention with electrical stimulation reduces neural damage after stroke in non-human primates
Authors: Zhou, J., Khateeb, K. and Yazdan-Shahmorad, A. Publication: Nature Communications Date: July 21, 2025 Abstract: For patients experiencing ischemic stroke, acute intervention offers the most critical therapeutic opportunity as it can reduce irreversible tissue injury and improve functional outcomes. However, currently available treatments within the acute window are highly limited and have strict patient…